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Bio-Informatics – Review on Current Research and Evolution of Cancer Targeted Therapies

by Ayan Chatterjee, Uttam Kumar Roy, Nibedita Pahari
Communications on Applied Electronics
Foundation of Computer Science (FCS), NY, USA
Volume 4 - Number 3
Year of Publication: 2016
Authors: Ayan Chatterjee, Uttam Kumar Roy, Nibedita Pahari

Ayan Chatterjee, Uttam Kumar Roy, Nibedita Pahari . Bio-Informatics – Review on Current Research and Evolution of Cancer Targeted Therapies. Communications on Applied Electronics. 4, 3 ( January 2016), 48-55. DOI=10.5120/cae2016652049

@article{ 10.5120/cae2016652049,
author = { Ayan Chatterjee, Uttam Kumar Roy, Nibedita Pahari },
title = { Bio-Informatics – Review on Current Research and Evolution of Cancer Targeted Therapies },
journal = { Communications on Applied Electronics },
issue_date = { January 2016 },
volume = { 4 },
number = { 3 },
month = { January },
year = { 2016 },
issn = { 2394-4714 },
pages = { 48-55 },
numpages = {9},
url = { },
doi = { 10.5120/cae2016652049 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
%0 Journal Article
%1 2023-09-04T19:53:28.930336+05:30
%A Ayan Chatterjee
%A Uttam Kumar Roy
%A Nibedita Pahari
%T Bio-Informatics – Review on Current Research and Evolution of Cancer Targeted Therapies
%J Communications on Applied Electronics
%@ 2394-4714
%V 4
%N 3
%P 48-55
%D 2016
%I Foundation of Computer Science (FCS), NY, USA

The statistics shows that 7 million people die each year worldwide from cancer related cases & by 2020 this number will be more than around 16 million as methods of cancer treatment & cancer classification have become most challenging. So, cancer has become a noted disease responsible for major death rate. 200 different types of cancers are identified but some of them like lung, liver, stomach, colorectal, breast, oesophagal are leading death count. More than 60% of world’s total new cases occur in Africa, Asia and Central and South America per annum. These regions account for 70% of the world’s cancer deaths by oesophagal cancers as reported by World Health Organization. This article reviews and discusses recent improvement in the treatment of cancer and the challenges that exist, in reduced cost & time. Development and use of bioinformatics, nanotechnology is essential for the future cancer therapeutics. Most cancer treatments work for limited number of patients and this is likely to remain true for many molecularly-targeted drugs. As a consequence, a large proportion of patients are deprived of effective treatments and it is a huge financial burden on our health care system. It is essential to develop accurate tools for delivering the right treatment to the right patient based on biological characterization of each patient's tumor. The integration of wet experiments and the use of bio-informatics analysis have become an important part of biological and clinical research of this century. If we don’t pay attention to it in future we will find a cancer patient in each family across the world. Cancer cure is really difficult but not complete hopeless. A lot of researches are being carried out in the field of bio-informatics to open up new possibilities for cancer treatments.

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Index Terms

Computer Science
Information Sciences


Ligand Microarray Target PDB cell cycle Oncogenes Tumor Peptide DNA/Gene Tumor Suppressor Kinase etc.